Assessment - SANS 10386 - Module 1 - ARCHIVED 260521 – Scientific Veterinary Consulting

Which ONE of the following statements regarding the governing principles of the SANS 10386 is INCORRECT?

Respect for animals should form the foundation of all decisions and actions of all people involved in the care and use of animals for scientific purposes

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The harm-benefit analysis should form an integral part of the formal assessment as to whether a proposed use of animals can be considered ethically acceptable

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The wellbeing of animals shall be supported through all stages of their care and use, and should be considered in terms of their cumulative lifetime experience

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High standards of scientific integrity shall be maintained by ensuring that animals are only used in studies that are well-justified with significant scientific merit, are feasible, well-designed and scientifically valid, carefully conducted so that there is a reasonable expectation that the aims of the project will be achieved, and only when alternatives (i.e. non-animal replacements) are not available

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Registration of all Animal Ethics Committees with the national regulatory body (NHREC) is essential to ensure that the composition, functioning, quality of ethical review, and oversight by the Committee meets the minimum standards of SANS 10386

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Which ONE of the following entities is the publisher of the SANS 10386?

South African Bureau of Standards

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National Research Foundation

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South African Medical Research Council

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National Department of Health

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Council for Scientific and Industrial Research

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Which ONE of the following options is an example of a “Reduction” in the use of animals?

Drawing the minimum volume of blood that is needed

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Using the minimum number of animals that are needed to produce valid results

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Injecting an animal only once, instead of multiple times

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Using euthanasia methods that cause the minimum amount of distress

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Ensuring that all people who work with animals understand their responsibilities

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Which ONE of the following options is NOT an example of a “Refinement” in the care and use of animals?

Ensuring that all of the people who capture, handle, or restrain animals, have been formally assessed and confirmed to be competent in these functions

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Keeping animals in confinement in conditions that are as similar as possible to their natural environments

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Restraining or performing procedures on animals less frequently

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Keeping animals in compatible groups (for social species), rather than keeping animals in isolation

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Using tissue culture to test whether a compound is toxic, before testing the compound on live animals, so that only the compounds that are not significantly toxic in tissue culture will as the next step be tested on live animals

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Which ONE of the following options is an example of a “Replacement” of the use of animals?

Using the minimum number of animals that are needed for a scientific study

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Limiting the overall amount of cumulative animal suffering in a scientific study

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Using cell culture models or computer simulations instead of using live animals

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Doing a statistical calculation (power analysis) to estimate the number of animals (sample size) needed for a specific study

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Ensuring that all of the people who capture, handle or restrain animals, or perform procedures on animals, are competent in doing so

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Which ONE of the following is one of the Four Rs (“4Rs”), as defined in the SANS 10386?

Respect

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Regulations

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Rights

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Responsibility

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Reproducibility

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Which ONE of the following statements regarding the SANS 10386 is INCORRECT?

Animal Ethics Committee approval is required for the use of animals in research or testing

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Animal Ethics Committee approval is required for the use of animals in teaching or training, including to teach non-invasive methods (e.g., behavioural studies)

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Animal Ethics Committee approval is required for the use of animals for scientific purposes, including agricultural animals, veterinary patients, and farm animals

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Animal Ethics Committee approval is required for the use of animals for scientific purposes in environmental or conservation studies

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Animal Ethics Committee approval is required for wildlife studies where animals are captured or restrained, but not for purely observational wildlife studies

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Which ONE of the following statements regarding the concept of animal “sentience” is CORRECT?

“Sentience” refers to an animal's relative level of intelligence

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“Sentience” refers to whether an animal is a vertebrate (i.e., with a backbone/spine) or an invertebrate (i.e., without a backbone/spine)

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“Sentience” refers to an animal's ability to reason or think

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“Sentience” refers to an animal's ability to feel or experience pleasures (positive affective states) and suffering (negative affective states)

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“Sentience” refers to an animal’s state of mental and physical wellbeing

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In which year was the current version of the SANS 10386 published?

2008

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2019

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2023

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2021

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2015

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Which ONE of the following statements regarding the SANS 10386 is INCORRECT?

Fish, frogs, crocodiles, lizards, birds, bats, mice, rats and cats are included in the definition of "animals", therefore the SANS 10386 requirements apply to them

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The SANS 10386 requires that researchers should submit proposals to use all invertebrates (including insects, worms, ticks and spiders) for consideration by Animal Ethics Committees

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The octopus, crab, squid, lobster (crayfish, kreef) and prawn are included in the definition of "animals", therefore the SANS 10386 requirements apply to them

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The SANS 10386 requires Animal Ethics Committee approval to use all animals and animal tissues for scientific purposes, including samples obtained from live animals, roadkill, museum specimens, and dead animals collected from nature

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The SANS 10386 requires Animal Ethics Committee approval for fish that are obtained from saltwater (e.g., oceans), freshwater (e.g., rivers) and farm dams

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Essence of the SANS 10386 (2021) – Online Short Course

Participants 372

Assessment – SANS 10386 – Module 1 – ARCHIVED 260521

Bert.Mohr 20 May 2024

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